- Healthcare Pharmaceuticals
- Mar 08
What are the Applications of ANOVA in the field of Healthcare and Pharmaceutical Industry?
Healthcare Industry is the largest sector in India which comprises of hospitals, pharmaceuticals, diagnostics, telemedicine, medical tourism and so on. We will discuss a few applications of ANOVA in the field of pharmaceutical and other health services. Before going to ANOVA, let us create some basic background and will be helpful to grasp in a wider way.
First of all, I would like to introduce the term called “Sampling”. Sampling plays an important role in healthcare data analysis, in fact in any kind of data analysis. It is a process of selecting a sample from a population for a specify study or analysis. For example, we want to conduct a study on a diabetes patient and here it is not possible to conduct a study on the whole population (say India) due to certain factors. So, what will we do? We will take a sample (say Karnataka, West Bengal, Rajasthan, Himachal Pradesh, Meghalaya) and do the study. By now, we must be clear about the concept of the sampling process.
Next, we will dig little on “Hypothesis testing” – based on a collected sample we need to draw inferences or to make a conclusion about the data, we need hypothesis testing. In simpler words, the process of drawing inferences (making decisions) about the sample with regards to the population as a whole is known as hypothesis testing.
Now, let’s discuss the basic sample tests viz. one sample t-test and two-sample t-test.
- One sample t-test – When we have one sample group, we will use one sample t-test.
- Two sample t-test – When we have two independent sample groups, we will use two-sample t-test.
Suppose in a Pharmaceutical Company, QA officer collects a two sample groups (A and B) each of 10 tablets to measure the dissolution rate of a drug. We can compare which of these types have a better dissolution rate and hence we able to choose the best one. Here, we apply a two-sample t-test.
By now we know the basic concepts of sample tests, when we have one sample, we use one sample t-test and when we have two sample groups, we use two-sample t-test. Isn’t it simple?
In many real-life scenarios, we will have more than two sample groups say three or four sample groups then “What can we do?” In this case, ANOVA comes into play. Finally……right
ANOVA (known as Analysis of Variance) is a technique which is used to check whether the means of two or more sample groups are statistically different or not.
Suppose in the Healthcare Industry, we can use the ANOVA test to compare different medications and the effect on patients. If a company has 3 different medications for treating ulcers and by using ANOVA, we can determine the effectiveness of treating them. We can compare which medication works better for treatment and hence we able to choose the best one.
During the vendor quality evaluation, we can use ANOVA to evaluate the quality of product supplies received from different vendors. Similarly, we can apply in various healthcare scenarios.
- Reference
Suppose in a Pharmaceutical Company, QA officer collects four sample groups (A, B, C & D) each of 6 tablets to measure the hardness of a tablet.
Since our p-value is 0.004 (From ANOVA Table) which is less than our alpha value 0.05, we can conclude that the means are significantly different from each other. Similarly, on an interval plot, we can see the mean differences between each type.
Let’s discuss a few of the assumption it holds.
- Data must be numerical in nature.
- The sample data (variable) should be independent.
- Data must follow a normal distribution.
NB – Want to learn the concepts of ANOVA and Application in Industries? Attend our Statistical Training Program starting from basic to advanced level. Some of the Statistical training certified courses are Predictive Analytics Masterclass, Essential Statistics For Business Analytics, SPC Masterclass, DOE Masterclass, etc. Apart from Statistical training, we also conduct Minitab Certified Training Program, starting from basic to advanced level. Some of the Minitab software training certified courses are Minitab Essentials, Statistical Tools for Pharmaceuticals, Statistical Quality Analysis & Factorial Designs, etc.
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